Investors across 15 countries will be approached about buying the iconic JW Marriott Grosvenor House Hotel in Park Lane, Mayfair, which has been put up for sale for around £500 million.
Property agent JLL, appointed by administrator Deloitte, will market the 494-bed property globally, including in North America, Asia and the Middle East.
The sale process was triggered after its owner Sahara Grosvenor House Hospitality failed to pay debts on the five-star hotel.
"The last hotel transaction on Park Lane took place two years ago and as the market has strengthened since then, we are looking forward to engaging with investors in an open marketing process," said Mark Wynne-Smith global chief executive at JLL's Hotels and hospitality group.
The offer comes amid an expected rush of dealmaking in the hotel market.
JLL has forecast that global hotel transaction volumes will reach an eight-year high of between $65 billion (£42 billion) and US$68 billion in 2015 - a 15% increase over last year.
